Berberine HCl supplies Berberine HCl isolated from Berberis vulgaris (barberry). Berberine has a long history of use in both Chinese and Ayurvedic medicine to support normal glucose and/or lipid metabolism and lipid levels. 
Berberine is a bitter-tasting alkaloid present in the roots,
rhizomes and stem barks of select plants including
Barberry (Berberis vulgaris). Berberine has a long
history of use in both Chinese and Ayurvedic medicine,
primarily to support gastrointestinal function. Berberine
has demonstrated significant activity against a wide
variety of organisms including a broad spectrum of
bacteria, yeasts, fungus and parasites. Its mechanism of
action is thought to result in part from its characteristic
structure, which is that of a planar cationic molecule.
This structural arrangement enables it to intercalate the
DNA structure, similar in fashion to the mechanism of
ethidium bromide.