Phosphatidylcholine has been implicated as the preferred source of choline for this action.6
Hepatic phosphatidylcholine is considered an important component in liver function as well as in metabolic regulation. A decrease in hepatic phosphatidylcholine has been associated with an accumulation of triglycerides in the liver, along with a reduced level of plasma lipids and plasma lipoprotein. In animal studies choline intake was correlated to a hepatoprotective effect. Consequently phosphatidylcholine supplementation in persons with liver impediments is particularly important. Biotics Research Corporation’s Phosphatidylcholine is supplied as a highly bioavailable form, which is well tolerated, odor free, readily absorbed and most importantly tested to ensure quality and purity. Choline plays a fundamental role in the synthesis of membrane phospholipid components of the cell membrane. Although choline may be synthesized in vivo, from either methionine or serine, it is
considered an essential nutrient.4 The composition of essential fatty
acids in phosphatidylcholine determines its value in promoting
health. Lowered blood choline is frequently displayed as liver steatosis (fatty liver) and related dysfunctions, and a deficiency in choline has been correlated with deleterious affects on the expression of a variety of
genes, including those involved in cell proliferation, cell differentiation
and apoptosis. Choline deficiency has also been associated with liver
dysfunction and neoplastic diseases, as well as with neurodegenerative disorders, including Alzheimer’s and Parkinson’s disease.5 A source
of choline contributes to the biosynthesis of the neurotransmitter
acetylcholine, a neurotransmitter which has many functions in the
body, including its involvement in muscle control and memory.